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. 2014 Nov 4;9(11):e109575. doi: 10.1371/journal.pone.0109575

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© 2014 Xia et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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A: Representative immunofluorescence staining results for OCT-4 expression in Yap- and Tead1/3/4-silenced OCICs. B-C: Real-time RT-PCR (B) and Western blotting (C) results showing that the indicated genes were down-regulated in OCICs after RNAi depletion of Yap and Tead1/3/4. D: Images of OCIC spherical clusters without (upper panels) and with (lower panels) shYap-treatment by 200 times magnification.