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. 2014 Nov 4;9(11):e109843. doi: 10.1371/journal.pone.0109843

Table 6. The AUCs (areas under the curves) analyzed by receiver operating characteristics (ROC) curves.

Diagnosis (or Differential Diagnosis) Area under the ROC curve (AUC) Statistical Significance (p) Asymptotic 95% Confidence Interval
Lower Bound Upper Bound
DD:. Healthy or abnormalities of the ocular surface 0.98 P <0.001 0.00 1.00
ATD 0.78 p<0.001 0.68 0.88
MGDs 0.66 p  = 0.013 0.53 0.78
DD:. ATD or MGDs 0.67 p  = 0.025 0.54 0.81
By applying the TDI (cutoff  =  1.35) in the 1.00 p <0.001 1.00 1.00
DD between ATD from MGDs

In this case, no abnormalities of the ocular surface (ATD + MGDs)  =  positive diagnosis.

DD =  differential diagnosis. ATD  =  aqueous tear deficiency; obstructive MGD  =  (obvious) obstructive meibomian gland dysfunction; NOMGD  =  non-obvious obstructive meibomian gland dysfunction; MGDs  =  obstructive MGD or NOMGD; ROC curves  =  (receiver operating characteristics) curves.