Table 4. Selected characteristics of the study patients with acute central nervous system infections classified by clinical diagnosis, country of Georgia.
Feature | Bacterial Meningitis (n = 75) | Viral Meningitis (n = 39) | Tuberculosis Meningitis (n = 8) | Encephalitis (n = 12) | P-value |
Age (years), mean (SD) | 28.8 (24.8) | 13.5 (16.8) | 40.4 (19.6) | 21.5 (15.7) | 0.004 |
Male | 39 (52) | 19 (50) | 5 (62) | 8 (67) | 0.717 |
Tbilisi residence | 29 (39) | 17 (44) | 4 (50) | 3 (25) | 0.633 |
Urban residence | 52 (69) | 28 (72) | 4 (50) | 4 (33) | 0.057 |
Animal contact | 21 (28) | 14 (36) | 3 (37) | 6 (50) | 0.450 |
Agriculture activity | 6 (8) | 2 (5) | 2 (25) | 4 (33) | 0.017 |
Duration of illness (days), mean (SD) | 4.8 (7.8) | 2.4 (2.2) | 3.6 (2.1) | 8.2 (4.8) | <0.001 |
Another infection in the prior month | 16 (21) | 2 (5) | 0 (0) | 3 (25) | 0.067 |
Hospitalized in the prior month | 27 (36) | 6 (15) | 4 (50) | 5 (42) | 0.064 |
Days of hospitalization, mean (SD) | 14.5 (6.2) | 9.3 (4.1) | 11.7 (8.5) | 17.3 (12.3) | <0.001 |
Kernig's sign | 45 (60) | 14 (37) | 6 (75) | 2 (17) | 0.005 |
Brudzinski's sign | 31 (41) | 17 (46) | 4 (50) | 2 (17) | 0.310 |
Altered state of consciousness | 21 (28) | 3 (8) | 2 (25) | 4 (33) | 0.090 |
Severe or moderate disability | 10 (14) | 1 (3) | 1 (12) | 2 (17) | 0.289 |
Motor deficit | 3 (4) | 3 (8) | 0 (0) | 5 (45) | <0.001 |
Chillls | 50 (70) | 23 (60) | 4 (50) | 2 (18) | 0.009 |
Change of personality | 17 (24) | 1 (3) | 1 (12) | 2 (18) | 0.040 |
Sleep disturbance | 42 (59) | 10 (26) | 4 (50) | 3 (27) | 0.006 |
Cranial nerve palsy | 2 (3) | 2 (5) | 2 (25) | 4 (36) | <0.001 |
Turbid CSF | 43 (58) | 1 (3) | 1 (12) | 0 (0) | <0.001 |
Illness resolved at hospital discharge | 62 (87) | 37 (95) | 2 (25) | 3 (25) | <0.001 |
Note: SD, standard deviation; CSF, cerebrospinal fluid.