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. 2014 Nov 4;9(11):e111393. doi: 10.1371/journal.pone.0111393

Table 4. Selected characteristics of the study patients with acute central nervous system infections classified by clinical diagnosis, country of Georgia.

Feature Bacterial Meningitis (n = 75) Viral Meningitis (n = 39) Tuberculosis Meningitis (n = 8) Encephalitis (n = 12) P-value
Age (years), mean (SD) 28.8 (24.8) 13.5 (16.8) 40.4 (19.6) 21.5 (15.7) 0.004
Male 39 (52) 19 (50) 5 (62) 8 (67) 0.717
Tbilisi residence 29 (39) 17 (44) 4 (50) 3 (25) 0.633
Urban residence 52 (69) 28 (72) 4 (50) 4 (33) 0.057
Animal contact 21 (28) 14 (36) 3 (37) 6 (50) 0.450
Agriculture activity 6 (8) 2 (5) 2 (25) 4 (33) 0.017
Duration of illness (days), mean (SD) 4.8 (7.8) 2.4 (2.2) 3.6 (2.1) 8.2 (4.8) <0.001
Another infection in the prior month 16 (21) 2 (5) 0 (0) 3 (25) 0.067
Hospitalized in the prior month 27 (36) 6 (15) 4 (50) 5 (42) 0.064
Days of hospitalization, mean (SD) 14.5 (6.2) 9.3 (4.1) 11.7 (8.5) 17.3 (12.3) <0.001
Kernig's sign 45 (60) 14 (37) 6 (75) 2 (17) 0.005
Brudzinski's sign 31 (41) 17 (46) 4 (50) 2 (17) 0.310
Altered state of consciousness 21 (28) 3 (8) 2 (25) 4 (33) 0.090
Severe or moderate disability 10 (14) 1 (3) 1 (12) 2 (17) 0.289
Motor deficit 3 (4) 3 (8) 0 (0) 5 (45) <0.001
Chillls 50 (70) 23 (60) 4 (50) 2 (18) 0.009
Change of personality 17 (24) 1 (3) 1 (12) 2 (18) 0.040
Sleep disturbance 42 (59) 10 (26) 4 (50) 3 (27) 0.006
Cranial nerve palsy 2 (3) 2 (5) 2 (25) 4 (36) <0.001
Turbid CSF 43 (58) 1 (3) 1 (12) 0 (0) <0.001
Illness resolved at hospital discharge 62 (87) 37 (95) 2 (25) 3 (25) <0.001

Note: SD, standard deviation; CSF, cerebrospinal fluid.