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. 2014 Nov 4;9(11):e111397. doi: 10.1371/journal.pone.0111397

Table 2. Characteristics of the study, baseline characteristics.

Mean age, year Mean baseline SCr (mg/dL) Mean baseline eGFR (ml/min)
Trial (Year) Statin Control Statin Control Statin Control Male proportion Diabetes Mellitus proportion Hypertension proportion Additional measures
PROMISS (2008) 65 66 1.29 1.25 53.46 55.40 72.5% 25.9% 63.2% None
Toso et al. (2009) 75 76 1.20 1.18 46.00 46.00 64.5% 21.1% 60.5% NAC
Xinwei et al. (2009) 65 66 0.82 0.83 86.50 93.60 36.0% 20.6% 63.6% None
Zhou Xia et al. (2009) 60 61 1.04 1.08 76.88 70.54 59.0% 20.0% 75.0% None
Acikel et al. (2010) 59 61 0.84 0.85 97.70 97.00 63.8% 24.4% 58.1% None
Ozhan et al. (2010) 54 55 0.88 0.88 92.00 89.00 59.2% 16.2% 22.3% NAC
Hua et al. (2010) 65 65 1.34 1.40 68.20 66.70 67.1% 26.6% 74.6% None
ARMYDA-CIN (2011) 65 66 1.04 1.04 79.80 77.00 77.6% 28.2% 75.1% None
Wei Li et al. (2012) 66 65 0.93 0.93 NR NR 75.8% 28.0% 80.7% None
NAPLES II (2012) 70 70 1.32 1.29 42.00 43.00 54.4% 41.2% 86.3% NAC, bicarbonate
CAO et al. (2012) 63 63 0.85 0.83 109.60 106.80 57.2% 21.7% 37.2% None
PRATO-ACS (2014) 66 66 0.95 0.96 69.90 69.30 65.7% 21.2% 55.8% NAC
TRACK-D (2014) 62 61 1.08 1.07 74.16 74.43 65.2% 100.0% 71.9% None

Abbreviations: ACS, acute coronary syndrome; CAG, coronary angiography; CIN, contrast induced nephropathy; CKD, chronic kidney disease; CrCl, creatinine clearance; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; LDL, low-density lipoprotein; LVEF, left ventricular ejection fraction; NAC, N-acetylcystein; NR, not reported; NS, normal saline (isotonic saline, 0.9%); NSTEMI, non ST-segment elevation myocardial infarction; PCI, percutaneous coronary intervention; SCr, serum creatinine; STEMI, ST-segment elevation myocardial infarction; UA, unstable angina.