Table 2. Characteristics of the study, baseline characteristics.
Mean age, year | Mean baseline SCr (mg/dL) | Mean baseline eGFR (ml/min) | ||||||||
Trial (Year) | Statin | Control | Statin | Control | Statin | Control | Male proportion | Diabetes Mellitus proportion | Hypertension proportion | Additional measures |
PROMISS (2008) | 65 | 66 | 1.29 | 1.25 | 53.46 | 55.40 | 72.5% | 25.9% | 63.2% | None |
Toso et al. (2009) | 75 | 76 | 1.20 | 1.18 | 46.00 | 46.00 | 64.5% | 21.1% | 60.5% | NAC |
Xinwei et al. (2009) | 65 | 66 | 0.82 | 0.83 | 86.50 | 93.60 | 36.0% | 20.6% | 63.6% | None |
Zhou Xia et al. (2009) | 60 | 61 | 1.04 | 1.08 | 76.88 | 70.54 | 59.0% | 20.0% | 75.0% | None |
Acikel et al. (2010) | 59 | 61 | 0.84 | 0.85 | 97.70 | 97.00 | 63.8% | 24.4% | 58.1% | None |
Ozhan et al. (2010) | 54 | 55 | 0.88 | 0.88 | 92.00 | 89.00 | 59.2% | 16.2% | 22.3% | NAC |
Hua et al. (2010) | 65 | 65 | 1.34 | 1.40 | 68.20 | 66.70 | 67.1% | 26.6% | 74.6% | None |
ARMYDA-CIN (2011) | 65 | 66 | 1.04 | 1.04 | 79.80 | 77.00 | 77.6% | 28.2% | 75.1% | None |
Wei Li et al. (2012) | 66 | 65 | 0.93 | 0.93 | NR | NR | 75.8% | 28.0% | 80.7% | None |
NAPLES II (2012) | 70 | 70 | 1.32 | 1.29 | 42.00 | 43.00 | 54.4% | 41.2% | 86.3% | NAC, bicarbonate |
CAO et al. (2012) | 63 | 63 | 0.85 | 0.83 | 109.60 | 106.80 | 57.2% | 21.7% | 37.2% | None |
PRATO-ACS (2014) | 66 | 66 | 0.95 | 0.96 | 69.90 | 69.30 | 65.7% | 21.2% | 55.8% | NAC |
TRACK-D (2014) | 62 | 61 | 1.08 | 1.07 | 74.16 | 74.43 | 65.2% | 100.0% | 71.9% | None |
Abbreviations: ACS, acute coronary syndrome; CAG, coronary angiography; CIN, contrast induced nephropathy; CKD, chronic kidney disease; CrCl, creatinine clearance; DM, diabetes mellitus; eGFR, estimated glomerular filtration rate; LDL, low-density lipoprotein; LVEF, left ventricular ejection fraction; NAC, N-acetylcystein; NR, not reported; NS, normal saline (isotonic saline, 0.9%); NSTEMI, non ST-segment elevation myocardial infarction; PCI, percutaneous coronary intervention; SCr, serum creatinine; STEMI, ST-segment elevation myocardial infarction; UA, unstable angina.