Skip to main content
. 2014 Nov 4;9(11):e111793. doi: 10.1371/journal.pone.0111793

Figure 7. Invertebrate host-induced pressure is specific to CpT (and not TpC) and CpG (and not GpC) dinucleotides.

Figure 7

(a) Box plot comparing the CpTO/E/TpCO/E ratios among large DNA viruses infecting invertebrates and vertebrates. The CpTO/E/TpCO/E ratios were significantly lower in large DNA viruses infecting invertebrates as compared to those infecting vertebrates (0.76±0.11 vs 0.93±0.14; P<0.0001) clearly demonstrating that CpT dinucleotides but not TpC dinucleotides are subjected to host-induced pressures. (b) Box plot comparing the relative CpGO/E/GpCO/E ratios dinucleotides among large DNA viruses infecting invertebrates and vertebrates. The CpGO/E/GpCO/E ratios among large DNA viruses infecting invertebrates were significantly higher than those infecting vertebrates (1.17±0.32 vs 1.06±0.28; P = 0.01), demonstrating that CpG dinucleotides but not GpC dinucleotides are subjected to host-induced pressures among large DNA viruses infecting invertebrate hosts.