Table 1. CpT and CpG dinucleotide frequencies: Genome-wide vs coding DNA sequences (CDS) among large DNA viruses infecting invertebrates.

	Genome-wideO/E ratio	CDS O/Eratio	Viruses with increased bias in the non-codingregion than in coding region (n)	Wilcoxon signedrank test
CpT dinucleotide	0.72±0.10	0.73±0.11	57	P = 0.002
CpG dinucleotide	1.41±0.29	1.39±0.28	73	P<0.0001