Table 1. Characteristics and biochemical parameters from Control and MS rats during aging. Values are mean±SEM. n=8. cP<0.01 vs Control at corresponding age. eP<0.05 vs 6 and 12 months of age in the same group, hP<0.05 vs 6 months of age in the same group.
| Control |
MS |
|||||
|---|---|---|---|---|---|---|
| 6 months | 12 months | 18 months | 6 months | 12 months | 18 months | |
| Body weight (g) | 516.2±8.5 | 573.3±19.6 | 616.3±12.8e | 526.2±14.3 | 649.3±50.7 | 817.3±30.9ce |
| Central adiposity (g) | 5.9±0.7 | 9.2±0.5 | 13.1±1.6e | 11.9±0.6c | 18.7±1.7c | 40.6±3.9ce |
| Blood pressure (mmHg) | 103.4±0.6 | 103.2±1.2 | 100.1±0.7 | 143.2±0.7c | 109.9±5.9c | 95.9±1.1ce |
| Glucose (mmol/L) | 5.9±0.3 | 5.2±0.2 | 5.6±0.4 | 4.8±0.7 | 6.1±0.4 | 6.3±0.2 |
| Triglycerides (mg/dL) | 55.6±4.7 | 93.2±6.3h | 155.8±8.9e | 109.1±12.8c | 200.4±30.3ch | 266.2±28.9ch |
| Insulin (μU/mL) | 6.5±0.9 | 6.5±2.4 | 6.4±0.7 | 18.2±3.5c | 17.4±6.7 | 7.5±1.6h |
| Leptin (ng/mL) | 1.0±0.2 | 3.5±0.6 | 3.5±0.5h | 3.9±0.5c | 10.8±1.9c | 20.2±2.6ce |
| Adiponectin (μg/mL) | 3.1±0.2 | 3.5±0.3 | 3.2±0.2 | 5.5±0.4c | 7.1±0.7c | 7.8±0.4ch |