Table 2. Cytokine concentrations in BAL fluid in mice after 3 d of CS exposure. Results are expressed as mean±SD. n=6 mice per group from at least two independent experiments. bP<0.05 vs CS-exposed mice. fP<0.01 vs air-exposed mice and rIL-22 pretreated mice.
CXCL9 (ng/L) | CXCL10 (pg/mL) | CXCL11 (ng/L) | IL-22 (pg/mL) | IL-8 (pg/mL) | IL-6 (ng/L) | TGFβ1 (ng/L) | TNFα (ng/L) | |
---|---|---|---|---|---|---|---|---|
Air | 66.33±5.40 | 101.15±4.86 | 44.46±4.15 | 74.53±0.73 | 58.39±7.79 | 87.74±6.96 | 127.06±5.32 | 343.78±29.95 |
IL-22 | 70.00±4.75 | 125.59±2.39 | 44.05±2.54 | 75.29±0.33 | 61.42±6.24 | 90.92±6.40 | 133.74±7.28 | 332.83±22.29 |
CS | 75.13±8.63f | 143.86±5.43f | 53.67±5.26f | 91.52±5.09f | 77.05±4.14f | 109.78±6.97f | 173.63±4.53f | 407.83±20.69f |
CS+IL-22 | 85.04±9.70b | 152.90±9.34b | 56.38±3.46 | 95.45±3.75b | 92.41±5.22b | 112.91±9.67 | 187.29±3.38b | 423.54±43.74b |