Table 1. TGR5 and FXR activities of triterpenoids. Data are presented as mean±SEM (n=3).

Name	TGR5		FXR
	EC50/nmol·L−1	Efficacy	EC50/nmol·L−1
GW4064	–	–	48.82±0.4
INT-777	395.1±125.6	100.0±0.7	NR
3α	1914±473.3	95.27±0.7	NR
3β	3214±385.6	83.15±4.0	NR

EC₅₀ and efficacy generated from human TGR5-based cAMP assay or human FXR-based reporter assay. NR=No response at concentrations up to 100 μmol/L.