Table 1.
Insertion site | (MIC mg/l) | Integration events | ||||
---|---|---|---|---|---|---|
ITR | POS | RAV | ||||
AF210 | - | - | 0.25 | 0.12 | 1.0 | - |
REMI 11 | ABC transporter | AFUA_1G14330 | 0.062 | 0.031 | 0.031 | 1 single REMI* |
REMI 56 | MFS transporter | AFUA_1G05010 | 0.062 | 0.031 | 0.25 | 1 single REMI* |
REMI 85 | Hypothetical gene | AFUA_5G07550 | 0.0078 | 0.031 | 0.062 | 1 single REMI# |
REMI 102 | Cyc8 | AFUA_2G11840 | 0.062 | 0.031 | 0.25 | 1 single REMI# |
REMI 14D | Triose phosphate isomerase | AFUA_2G11020 | 8.0 | 1.0 | 8.0 | 1 single REMI# |
REMI 101 | 29.9KD NADH dehydrogenase | AFUA_2G10600 | 1.0 | 0.50 | 4.0 | 1 single REMI* |
REMI 103 | Hypothetical gene | AFUA_4G10880 | 1.0 | 0.50 | 4.0 | 1 single REMI# |
REMI 116 | Epsin2 | AFUA_6G12570 | 1.0 | 0.50 | 4.0 | 2 single REMI |
insertion at intact XhoI site.
insertion at degenerate XhoI site.
ITR, itraconazole, POS, posaconazole, RAV, ravuconazole