(a) Primary structure of CFMO, with secondary structure assignment, created using DSSP [32], [33] and represented using ALINE [34]. (b) Structure of dimer of CFMO, in ribbon format, with subunit A in green and B in coral. One FAD molecule per monomer is shown in cylinder format with carbon atoms in grey. Helix α8, which forms part of the flexible helix–loop–helix structure that may shield the active site from bulk solvent, is also highlighted. (For interpretation of the references to color in this figure legend, the reader is referred to the web version of this article.)