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. 2014 Nov;109:191–198. doi: 10.1016/j.molcatb.2014.08.019

Table 3.

Results of biotransformations of prochiral sulfide substrates 1 and 3–6 by CFMO or PSFMO using either NADH or NADPH as nicotinamide cofactor. Values for SMFMO, reproduced from Ref. [10] are also given for comparison.

Sulfide NADH
NADPH
Conversion (%); absolute configuration; e.e.
Conversion (%); absolute configuration; e.e. (%)
SMFMO* CFMO PSFMO SMFMO* CFMO PSFMO
1 27, (R)-, 71% e.e. 17, (R)-, 54% e.e. 61, (R)-, 30% e.e. 2, (R)-, 57% e.e. 6, (S)-, 43% e.e. 28, (R)-, 24% e.e.
3 90, (R)-, 25% e.e. 65, (R)-, 22% e.e. 97, (R)-, 47% e.e. 33, (R)-, 44% e.e. 32, (R)-, 32% e.e. 78, (R)-, 32% e.e.
4 8, (R)-, 21% e.e. 64, (R)-, 58% e.e. 99, (R)-, 14% e.e. 1, n.d. 38, (R)-, 64% e.e. 73, (S)-, 4% e.e.
5 6, (S)-, 15% e.e. No conversion 13, (S)-, 10% e.e. <1, n.d. 11, (R)-, 3% e.e. No conversion
6 40, (R)-, 80% e.e. 14, (R)-, 66% e.e. 50, (R)-, 85% e.e. 9, (R)-, 82% e.e. 47, (R)-, 77% e.e. 22, (R)-, 57% e.e.
*

Data taken from Ref. [10].

n.d. = not determined.