Table 1.
Clinical characteristics in 4896 patients in five trials in meta-analysis of effects of bare metal stent (BMS) or cobalt-chromium everolimus eluting stents (DES) on fatal and non-fatal cardiovascular events. Figures are numbers (percentages) unless stated otherwise
| Overall (n=4896) | PRODIGY | EXAMINATION | BASKET PROVE | SPIRIT I | XIMA | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| BMS (n=502) | DES (n=501) | BMS (n=747) | DES (n=751) | BMS (n=765) | DES (n=774) | BMS (n=29) | DES (n=27) | BMS (n=401) | DES (n=399) | ||||||
| Mean (SD) age (years) | 67 (13) | 68.9 (11.2) | 68.1 (11.3) | 61.6 (12.6) | 60.8 (12.2) | 64.1 (10.8) | 63.6 (10.7) | 61.4 (9.3) | 64.2 (9.6) | 83.4 (3.1) | 83.6 (3.2) | ||||
| Female | 1200 (24.5) | 139 (27.7) | 107 (21.4) | 137 (18.3) | 117 (15.6) | 179 (23.4) | 187 (24.2) | 7 (24.1) | 8 (29.6) | 164 (40.9) | 155 (38.8) | ||||
| Diabetes | 914 (18.7) | 111 (22.1) | 113 (22.5) | 121 (16.2) | 137 (18.3) | 108 (14.1) | 119 (15.4) | 3 (10.3) | 3 (11.1) | 97 (24.2) | 102 (25.6) | ||||
| Smoking habit: | |||||||||||||||
| Current smoker | 1581 (32.3) | 126 (25.2) | 117 (23.4) | 386 (51.7) | 372 (49.6) | 261 (34.1) | 267 (34.5) | 9 (31.0) | 7 (25.9) | 16 (3.9) | 20 (5.0) | ||||
| Former smoker | 1323 (27.0) | 101 (20.2) | 124 (24.8) | 152 (20.3) | 172 (22.9) | 203 (26.5) | 229 (29.6) | 7 (24.1) | 2 (7.4) | 168 (41.9) | 165 (41.3) | ||||
| Never | 1987 (40.6) | 272 (54.5) | 259 (51.8) | 209 (27.9) | 206 (27.5) | 301 (39.3) | 278 (35.9) | 13 (44.8) | 18 (66.7) | 217 (54.1) | 214 (53.6) | ||||
| Hypertension | 3055 (62.4) | 376 (74.9) | 356 (71.1) | 378 (50.6) | 347 (46.3) | 485 (63.4) | 469 (60.6) | 15 (51.7) | 19 (70.4) | 311 (77.6) | 299 (75.1) | ||||
| Hypercholesterolaemia | 2680 (54.7) | 254 (50.6) | 294 (58.7) | 301 (40.3) | 354 (47.2) | 495 (64.7) | 498 (64.3) | 22 (75.9) | 20 (70.1) | 212 (52.9) | 230 (57.6) | ||||
| Previous MI | 724 (14.8) | 114 (22.8) | 143 (28.7) | 47 (6.3) | 33 (4.4) | 100 (13.1) | 82 (10.6) | 0 | 0 | 86 (21.5) | 119 (29.8) | ||||
| Previous CABG | 201 (4.1) | 45 (8.9) | 61 (12.2) | 7 (0.9) | 3 (0.4) | 20 (2.6) | 20 (2.6) | 0 | 0 | 17 (4.2) | 28 (7.0) | ||||
MI=myocardial infarction; CABG=coronary artery bypass grafting.