Table 4.
Performance in CKD-EPI External Validation Dataset (US and Europe) by Race-Ethnicity
| Measures | Equation | Total | White and other | Black | Asian | Native American and Hispanic |
|---|---|---|---|---|---|---|
| N | 4014 | 3378 | 384 | 67 | 185 | |
| Bias ml/min/1.73 m | 2-level | 2.5 (2.1,2.9) | 2.8 (2.4,3.2) | −0.8 (−2.0,0.6) | 2.1 (0.3,4.4) | 2.3 (−2.1,5.1) |
| 4-level | 2.5 (2.1,2.9) | 2.9 (2.5,3.4) | −0.9 (−2.0,0.6) | 0.8 (−2.2,2.6) | 1.6 (−3.0,4.2) | |
| IQR, ml/min/1.73 m2 | 2-level | 17.0 (16.1,17.6) | 16.8 (16.0,17.6) | 15.1 (12.6,17.6) | 10.5 (8.0,14.6) | 25.6 (20.8,32.0) |
| 4-level | 17.0 (16.2,17.6) | 16.8 (16.0,17.6) | 15.1 (12.6,17.6) | 12.3 (9.0,16.1) | 26.1 (20.8,32.2) | |
| P30, % | 2-level | 84 (83,85) | 84 (83,86) | 82 (78,85) | 85 (76,93) | 80 (74,85) |
| 4-level | 84 (83,85) | 84 (83,85) | 82 (80,85) | 85 (76,93) | 81 (76,87) | |
| RMSE | 2-level | 0.250(0.242,0.259) | 0.250 (0.240,0.258) | 0.242(0.221,0.265) | 0.302(0.188,0.436) | 0.265(0.223,0.310) |
| 4-level | 0.250(0.242,0.259) | 0.250 (0.240,0.259) | 0.243(0.221,0.266) | 0.293(0.178,0.424) | 0.264(0.222,0.310 | |
Bias is calculated as measured GFR - estimated GFR; Interquartile range (IQR) refers to the 25–75th percentile; P30 refers to the percentage of GFR estimates that are within 30% of measured GFR; RSME is the root mean square error. Numbers in brackets are 95% confidence intervals.
To convert GFR from mL/min/1.73 m2 to mL/s/1.73 m2, multiply by 0.0167.