Table 2.
The efficacy of pharmacological drugs in COL4A3 -/- mice
| Drug | Survival (d) | Efficacy |
| Vasopeptidase inhibitor[22] | 172 | (+++) |
| ACE inhibitor[23] | 150 | (+++) |
| ARB[24] | 98 | (++) |
| HMG-CoA reductase inhibitor[26] | 91 | (++) |
| CCR1 inhibitor[27] | 86 | (+) |
| TNF-alpha antagonist[29] | 81 | (+) |
| Renin inhibitor[30] | 78 | (+) |
| Vitamin D analog[31] | 75 | (+) |
| Untreated (129SvJ background) | 71 |
ACE: Angiotensin converting enzyme; ARB: Angiotensin-II receptor blocker; CCR1: Chemokine (CC motif) receptor 1; HMG-CoA: 3-hydroxy-3-methylglutaryl-coenzyme A; TNF: Tumor necrosis factor.