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. 2014 Jun 18;2014(2):62–78. doi: 10.5339/gcsp.2014.29

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© 2014 Chester, Yacoub, licensee Bloomsbury Qatar Foundation Journals.

This is an open access article distributed under the terms of the Creative Commons Attribution license CC BY 4.0, which permits unrestricted use, distribution and reproduction in any medium, provided the original work is properly cited.

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Figure 6. — Signalling pathways linked to the conractile, migartory, proliverative and fate of cells mediated by ETA and ETB receptors. (PLC, phospholipase C; IP3, phosphatidylinositol; DAG, diacylglycerol; IP3 Ca²⁺, calcium ions; PKC, protein kinase C; MAPK, mitogen-activated protein kinase; PLD, phospholipase D; RTK, receptor tyrosine kinase; PI3K, phosphatidylinositol 3-kinase, cSRC, cytosolic tyrosine kinase; SHC, Src homology 2 domain-containing; GRB2, Growth factor receptor-bound protein 2; and SOS, Son of sevenless proetin; RAS, rat sarcoma protein; RAF, Rapidly Accelerated Fibrosarcoma protein).