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Effects of prophylactic administration of goshajinkigan (GJG), hachimijiogan (HJG), and rokumigan (RMG) on paclitaxel-induced mechanical allodynia. Paclitaxel (5 mg/kg) was injected intraperitoneally in mice, and GJG (a), HJG (b), RMG (c), or vehicle (5% gum arabic) was administered orally once daily from the day after the paclitaxel injection. Data are presented as mean and standard error of the mean (n = 5-6). *P < 0.05 compared to vehicle (Holm-Sidak multiple comparisons)
