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A) Effect of APcK110 and SCF on normal marrow CFU-GM. B) and C) Effect of APcK110 and SCF on AML marrow leukemia blast colony-forming cells. Figure B shows experiments without SCF in the presence and absence of APcK110. In figure C, AML cells are incubated with 50 nM of SCF and increasing concentrations of APcK110. CFU-GM and AML-CFU are presented as percent of control (50 nM SCF and no APcK110).
