Figure 1.

Light microscopic and ultrastructural findings in anabolic androgenic steroids abusers with FSGS. (A) A glomerulus shows collapsing focal sclerosis with retraction of the glomerular tuft and hyperplasia of overlying epithelial cells (arrow) (periodic acid-Schiff; original magnification, ×400). (B) A discrete lesion of segmental sclerosis is identified at the glomerular vascular pole (periodic acid-Schiff; original magnification, ×400) (C) A markedly hypertrophied glomerulus showing the unusual combination of a perihilar lesion of segmental sclerosis with collapsing features (periodic acid-Schiff; original magnification, ×400). (D) Electron micrograph showing >50% podocyte foot process effacement (original magnification, ×8000).