Table 2.
Association between MeDi score and incident eGFR<60 ml/min per 1.73 m2
| MeDi Score | OR (95% CI) | P Value |
|---|---|---|
| Continuous (per 1-point increase in MeDi score) | ||
| Unadjusted | 0.81 (0.72 to 0.92) | 0.002 |
| Demographic adjusteda | 0.83 (0.73 to 0.95) | <0.01 |
| Fully adjustedb | 0.83 (0.71 to 0.96) | 0.02 |
| MeDi score ≥5 (versus <5) | ||
| Unadjusted | 0.49 (0.33 to 0.75) | 0.001 |
| Demographic adjusteda | 0.49 (0.32 to 0.75) | 0.001 |
| Fully adjustedb | 0.50 (0.31 to 0.81) | 0.004 |
| MeDi quartiles (unadjusted) | ||
| 0–3 | Ref | |
| 4 | 1.30 (0.78 to 2.16) | 0.31 |
| 5 | 0.52 (0.28 to 0.95) | 0.03 |
| 6–9 | 0.60 (0.34 to 1.07) | 0.08 |
| MeDi quartiles (demographic adjusted) | ||
| 0–3 | Ref | |
| 4 | 1.44 (0.85 to 2.46) | 0.18 |
| 5 | 0.50 (0.27 to 0.93) | 0.03 |
| 6–9 | 0.67 (0.37 to 1.21) | 0.18 |
| MeDi quartiles (fully adjusted) | ||
| 0–3 | Ref | |
| 4 | 1.61 (0.88 to 2.97) | 0.12 |
| 5 | 0.51 (0.26 to 1.02) | 0.06 |
| 6–9 | 0.76 (0.39 to 1.46) | 0.41 |
OR, odds ratio; 95% CI, 95% confidence interval.
Adjusted for age (years), sex, race (black, white, Hispanic, or other), education (high school completion versus not), and insurance status (Medicare/private insurance versus Medicaid/no insurance).
Adjusted for age (years), sex, race/ethnicity (black, white, Hispanic, or other), education (high school completion versus not), insurance status (Medicare/private insurance versus Medicaid/no insurance), physical activity (any exercise versus not), BMI (kg/m2), diabetes (yes or no), smoking status (never, past, or current), hypertension (yes or no), LDL (mg/dl), HDL (mg/dl), baseline eGFR (ml/min per 1.73 m2), and ACE inhibitor/ARB usage (yes or no).