Table 1.

Summary of data from chronic rodent studies investigating the effects of RS on body weight and composition (chronological order). All data relative to animals fed DS. A blank cell indicates that this data was not collected.

RS effect on:		Duration (weeks)	Body Weight	Energy Intake	TEE	RQ	Body Fat/ Fat Pad Wt	LBM	Adipocyte Size
Lerer-Metzger et al (Lerer-Metzger, Rizkalla et al. 1996)		5	↓	= (*)			=		↓
Kabir et al (Kabir, Rizkalla et al. 1998)		3	=	= (*)			=		↓
Shen et al (Shen, Keenan et al. 2009)		9	= / = disemb	=			↓ by 8.3%
So et al (So, Yu et al. 2007)		8	=	↓			↓ by 33%		↓
Zhou et al (Zhou, Martin et al. 2008)
Healthy mice		16	= / ↓ disemb	↑	=	↓	↓ by 24% RS2 ↓ by 36% RS3
Obese mice		16	=	↑	=	↓	=
Pawlak et al (Pawlak, Bryson et al. 2001)
Expt 1, healthy rats		18	=	Controlled			↓ by 41%	↑
Expt 2, obese mice		9	=				↓ by 45%	↑
Pawlak (Pawlak, Kushner et al. 2004)		9	=				↓ by 22%
Scribner et al ((Scribner, Pawlak et al. 2008)		40	=	=	=	↓	↓ by 40%
Coate & Huggins ((Coate and Huggins)2010)		16	=	= (*)			↓ by 24% on LFD not HFD
Fukushima et al ((Fukushima, Ohashi et al. 2001))		4	=	= (◆)
Shimotoyodome et al (Shimotoyodome, Suzuki et al.) 2010)
Experiment 1		24	= (#^)	= (#^)			= (^) ↓ (#)
Experiment 2		24	↓ (^)	= (^)			↓ (^)
Experiment 3		0.75			↑ (#)	↓(#)
Higgins et al (Higgins, Jackman et al. 2011)		9	↓	↓ for 2 weeks then =	=		↓ by 20%	↑ 10%	↓

LBM, fat free mass (i.e. lean body mass)

disemb, disemboweled body weights

RQ, respiratory quotient. Lower RQ represents higher fat oxidation.

^#RS4 effects relative to RS2 NOT DS (TEE and RQ only reported for RS2 vs RS4 not for DS)

^{^}RS4 effects relative to DS (RS2 not reported in experiment 2)

^*Food intake was estimated in grams without taking into consideration the energy of the diets (RS had lower energy density).

^◆RS3 vs DS