Table 3. MP and fetal microchimerism1 in women with recurrent miscarriage and subsequent pregnancy.
Subject # | Gravidity/parity | Outcome | Clinical notes | Source of microchimerism | Preconception | First trimester5 | Second trimester | Third trimester | 6 weeks post | 6 months post |
---|---|---|---|---|---|---|---|---|---|---|
1 | 4/0 | 39 WGA2 live birth | Vaginal delivery, female, 3725 g | MP3 | 0.13 | 0, 0 | 6.77 | 0 | 0 | 0 |
2 | 3/0 | 39 WGA live birth | Vaginal delivery, male, 3155 g | MP | 0 | 0 | 0 | |||
3 | 4/0 | 34 WGA live birth | Cesarean section, female, 1956 g preeclampsia, neonatal demise | MP | 0 | 0, 1.43 | 0.69 | 0 | ||
4 | 6/0 | 40 WGA live birth | Vaginal delivery, male, 3941 g | MP | 0 | 0 | 0 | |||
5 | 5/0 | 39 WGA live birth | Vaginal delivery, male, 3147 g | MP | 0.16, 0 | 0 | 0 | |||
6 | 4/0 | 39 WGA live birth | Cesarean section, female, 3630 g | MP | 0, 0 | 15.32 | ||||
7 | 6/0 | 39 WGA live birth | Cesarean section, female, 4438 g | MP or fetal | 0 | 0 | 0 | 0 | ||
8 | 4/0 | 40 WGA live birth | Cesarean section, female, 2665 g, gestational hypertension | MP | 0 | 0, 0 | 0 | 0 | 1.55 | 0 |
MP or fetal | 0 | 0 | 0 | 0 | 0 | |||||
Fetal | 0 | 0.97 | 0 | 0 | ||||||
9 | 4/0 | 36 WGA live birth | Twins, Cesarean section, male/female, 2438 g/2750 g | MP or fetal | 0, 0 | 0 | 0 | |||
Fetal | 0, 3.39 | 0 | 0 | 0 | 0 | |||||
10 | 4/0 | 6 WGA2 miscarriage | MP3 | 0, 0, 0 | 0 | 0 | ||||
11 | 12/0 | 6 WGA miscarriage | MP or fetal | 0 | 0, 0 | 2.56 | 0 | |||
12 | 4/0 | 41 WGA live birth | Cesarean section, female, 3799 g | Fetal | 0 | 0, 0 | 0 | 0 | 0 | 0 |
13 | 3/0 | 39 WGA live birth | Vaginal delivery, female, 3657 g | Fetal4 | 0 | 0, 0 | 0 | 0 | 0 | |
14a6 | 5/0 | 8 WGA miscarriage | Fetal | 0 | 0, 0 | 0 | 0 | |||
14b6 | 6/0 | 6 WGA miscarriage | Fetal | 0, 0 | 0, 0.35 | 0.89 |
In GEq of microchimerism per total 100 000 GEq tested.
Weeks gestational age (WGA).
For these subjects, partner or child HLA typing not available to definitively rule out fetal source.
For these subjects, MP HLA typing not available to definitively rule out MP source.
Some subjects had more than one sample tested during the first trimester; these are all listed and delimited by commas.
For subject #14, two pregnancies were followed, and results are listed.