Table 2.
Survival parameters and RBE values for normal human fibroblasts irradiated at three depths in a 60-MeV SOBP
| Irradiation | α (Gy−1) | β (Gy−2) | SF2 | RBE SF = 0.37 |
RBE SF = 0.1 |
RBE SF = 0.01 |
|---|---|---|---|---|---|---|
| HFIB 2 | ||||||
| 6-MV X-rays | 0.582 ± 0.148 | 0.052 ± 0.008 | 0.24 ± 0.03 | |||
| SOBP 2 mm | 0.620 ± 0.159 | 0.041 ± 0.018 | 0.26 ± 0.07 | 1.04 ± 0.10 | 1.01 ± 0.07 | 0.98 ± 0.06 |
| SOBP 15 mm | 0.686 ± 0.273 | 0.035 ± 0.029 | 0.24 ± 0.10 | 1.11 ± 0.13 | 1.07 ± 0.08 | 1.02 ± 0.03 |
| SOBP 27 mm | 0.772 ± 0.177 | 0.026 ± 0.020 | 0.19 ± 0.08 | 1.23 ± 0.22 | 1.15 ± 0.15 | 1.06 ± 0.08 |
| HFIB 15 | ||||||
| 6-MV X-rays | 0.446 ± 0.129 | 0.065 ± 0.010 | 0.28 ± 0.06 | |||
| SOBP 2 mm | 0.500 ± 0.014 | 0.054 ± 0.018 | 0.31 ± 0.09 | 1.07 ± 0.21 | 1.04 ± 0.17 | 1.00 ± 0.15 |
| SOBP 15 mm | 0.493 ± 0.098 | 0.054 ± 0.021 | 0.32 ± 0.09 | 1.06 ± 0.11 | 1.02 ± 0.11 | 1.00 ± 0.13 |
| SOBP 27 mm | 0.561 ± 0.100 | 0.065 ± 0.032 | 0.25 ± 0.04 | 1.19 ± 0.14 | 1.14 ± 0.17 | 1.11 ± 0.10 |
| HFIB 30 | ||||||
| 6-MV X-rays | 0.814 ± 0.125 | 0.042 ± 0.018 | 0.25 ± 0.06 | |||
| SOBP 2 mm | 0.861 ± 0.112 | 0.038 ± 0.016 | 0.18 ± 0.03 | 1.02 ± 0.10 | 0.99 ± 0.07 | 0.95 ± 0.05 |
| SOBP 15 mm | 0.894 ± 0.125 | 0.031 ± 0.006 | 0.17 ± 0.02 | 1.05 ± 0.05 | 1.01 ± 0.02 | 0.97 ± 0.00 |
| SOBP 27 mm | 1.096 ± 0.141 | 0.010 ± 0.010 | 0.13 ± 0.03 | 1.24 ± 0.10 | 1.16 ± 0.06 | 1.05 ± 0.03 |
Listed are mean values ± SD from 3 to 4 independent experiments