Table 2.

Type I error for rare variant sets

Algorithm	$\alpha ={10}^{-5}$	$\alpha ={10}^{-4}$	$\alpha ={10}^{-3}$
Gaussian phenotype
Linear score	9.9 × 10−6	1.0 × 10−4	9.7 × 10−4
Linear LR test	6.9 × 10−6	1.1 × 10−4	1.0 × 10−3
Binary phenotype
Linear score	1.4 × 10−5	9.6 × 10−5	9.7 × 10−5
Linear LR test	1.6 × 10−5	1.0 × 10−4	9.8 × 10−4
Logistic score	1.4 × 10−5	9.9 × 10−5	1.0 × 10−3

No statistically significant deviations from expectation according to binomial test with significance level of 0.05.