Table 3. Correlations between change of epithelial and mesenchymal markers and clinicopathological variables.
Loss of | Gain of | Overall | |||||
---|---|---|---|---|---|---|---|
ZO-1 | E-cadherin | Vimentin | N-cadherin | Fibronectin | |||
Age (year) | |||||||
<10 | 3 | 5 | 4 | 4 | 29 | 51 | |
≥10 | 21 | 16 | 17 | 7 | 45 | 68 | |
P | 0.002b) | 0.09 | 0.03a) | 0.89 | 0.3 | ||
Body weight (kg) | |||||||
<10 | 16 | 14 | 13 | 9 | 49 | 82 | |
≥10 | 8 | 7 | 8 | 2 | 25 | 37 | |
P | 0.99 | 0.99 | 0.61 | 0.53 | 0.42 | ||
Ovarian status | |||||||
spayed | 6 | 4 | 5 | 1 | 11 | 16 | |
intact | 18 | 17 | 16 | 10 | 63 | 103 | |
P | 0.13 | 0.63 | 0.24 | 0.98 | 0.76 | ||
Experience of mastectomy | |||||||
first | 14 | 15 | 12 | 6 | 55 | 88 | |
experienced | 10 | 6 | 9 | 5 | 19 | 103 | |
P | 0.09 | 0.99 | 0.1 | 0.24 | 0.9 | ||
Tumor size (cm) | |||||||
<3 | 9 | 8 | 7 | 2 | 36 | 60 | |
≥3 | 8 | 7 | 14 | 2 | 25 | 37 | |
P | 0.23 | 0.32 | 0.14 | 0.054 | 0.62 | ||
Clinical stage | |||||||
I–III | 20 | 14 | 17 | 8 | 64 | 106 | |
IV and V | 4 | 7 | 4 | 3 | 10 | 13 | |
P | 0.52 | 0.001b) | 0.35 | 0.19 | 0.39 | ||
Histopathological type | |||||||
benign | 3 | 7 | 2 | 1 | 46 | 71 | |
malignant | 21 | 14 | 19 | 10 | 28 | 48 | |
P | <0.001b) | 0.014a) | <0.001b) | 0.001b) | 0.48 |
a) P<0.05, b) P<0.01.