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. 2014 Jun 16;76(10):1321–1327. doi: 10.1292/jvms.14-0104

Table 3. Correlations between change of epithelial and mesenchymal markers and clinicopathological variables.

Loss of Gain of Overall


ZO-1 E-cadherin Vimentin N-cadherin Fibronectin
Age (year)
<10 3 5 4 4 29 51
≥10 21 16 17 7 45 68
P 0.002b) 0.09 0.03a) 0.89 0.3
Body weight (kg)
<10 16 14 13 9 49 82
≥10 8 7 8 2 25 37
P 0.99 0.99 0.61 0.53 0.42
Ovarian status
spayed 6 4 5 1 11 16
intact 18 17 16 10 63 103
P 0.13 0.63 0.24 0.98 0.76
Experience of mastectomy
first 14 15 12 6 55 88
experienced 10 6 9 5 19 103
P 0.09 0.99 0.1 0.24 0.9
Tumor size (cm)
<3 9 8 7 2 36 60
≥3 8 7 14 2 25 37
P 0.23 0.32 0.14 0.054 0.62
Clinical stage
I–III 20 14 17 8 64 106
IV and V 4 7 4 3 10 13
P 0.52 0.001b) 0.35 0.19 0.39
Histopathological type
benign 3 7 2 1 46 71
malignant 21 14 19 10 28 48
P <0.001b) 0.014a) <0.001b) 0.001b) 0.48

a) P<0.05, b) P<0.01.