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. Author manuscript; available in PMC: 2015 May 1.
Published in final edited form as: Mucosal Immunol. 2014 Mar 26;7(6):1340–1353. doi: 10.1038/mi.2014.21

Figure 2. Cl-2TG mice are protected from DSS-induced acute colitis.

Figure 2

To induce colitis, mice received DSS (4% w/v) in the drinking water (10 days). (A). Weight loss during the course of DSS administration; (B). Disease activity index (DAI) changes among DSS-treated groups; C(i). Colon length (cm) in control and DSS-treated mice, C(ii). Representative colon images, and C(iii). Colon weight/cm; (D). Cumulative injury scores. Control mice did not show inflammation and associated injury; (E). Representative H&E staining of the colonic tissues from control and DSS-treated mice; (F). Representative photomicrographs demonstrating immunostaining to determine colonic myeloperoxidase (MPO) activity from control and DSS-treated mice. Values are presented as mean ± sem. *p<0.05, **p<0.01, ***p<0.001. Scale bars=500 or 50 μm.