Table 2.
Brain activation during (a) self-ascription (SELF) vs lexical processing of positive and negative personality traits, (b) ascription of positive and negative personality characteristics to the intimate other (OTHER) vs lexical processing, (c) the conjunction of SELF vs lexical processing and OTHER vs lexical processing, and (d) SELF vs OTHER in healthy subjects and schizophrenia patients with no activation for the opposite contrast (OTHER vs SELF) in both groups (flexible factorial analysis, P < 0.05 Monte Carlo corrected for multiple comparisons, MNI coordinates)
| Region | Side | x | y | z | kE | t |
|---|---|---|---|---|---|---|
| (a) SELF > lexical | ||||||
| Controls | ||||||
| Superior medial prefrontal cortex | L | −3 | 59 | 20 | 471 | 5.54 |
| Inferior orbitofrontal gyrus | L | −43 | 30 | −17 | 353 | 5.11 |
| Superior temporal pole (BA38) | R | 40 | 20 | −33 | 114 | 4.41 |
| Precuneus, posterior cingulate gyrus (BA30) | L | −3 | −53 | 20 | 79 | 4.47 |
| Middle temporal gyrus | L | −50 | −10 | −20 | 16 | 3.97 |
| Schizophrenia patients | ||||||
| Superior medial prefrontal gyrus | L | −13 | 46 | 46 | 413 | 7.37 |
| Inferior orbitofrontal gyrus | L | −46 | 30 | −17 | 108 | 7.24 |
| Precuneus, posterior cingulate gyrus (BA31) | L | −3 | −56 | 30 | 51 | 4.32 |
| Lingual gyrus (BA19) | L | −10 | −59 | −3 | 33 | 3.91 |
| (b) OTHER > lexical | ||||||
| Controls | ||||||
| Superior medial prefrontal cortex | L | −3 | 56 | 33 | 477 | 5.31 |
| Inferior orbitofrontal gyrus | L | −50 | 30 | −13 | 98 | 4.59 |
| Precuneus, posterior cingulate gyrus (BA30) | L | −3 | −53 | 20 | 137 | 4.72 |
| Schizophrenia patients | ||||||
| Superior prefrontal gyrus (BA8) | L | −13 | 46 | 49 | 140 | 6.29 |
| Inferior orbitofrontal gyrus | L | −43 | 30 | −17 | 56 | 4.55 |
| (c) Conjunction of SELF > lexical and OTHER > lexical | ||||||
| Controls | ||||||
| Superior medial prefrontal cortex | 0 | 56 | 20 | 374 | 5.25 | |
| Inferior orbitofrontal gyrus | L | −50 | 30 | −13 | 93 | 4.59 |
| Precuneus (BA30) | L | −3 | −53 | 20 | 59 | 4.47 |
| Schizophrenia patients | ||||||
| Superior prefrontal gyrus (BA8) | L | −13 | 46 | 49 | 140 | 6.29 |
| Inferior orbitofrontal gyrus | L | −43 | 30 | −17 | 55 | 4.55 |
| (d) SELF > OTHER | ||||||
| Controls | ||||||
| Superior temporal pole (BA38) | R | 46 | 20 | −30 | 23 | 4.13 |
| Gyrus rectus (BA25), parahippocampus | L | −3 | 20 | −20 | 23 | 3.79 |
| Parahippocampus | L | −20 | −10 | −33 | 16 | 3.66 |
| Schizophrenia patients | ||||||
| Superior medial prefrontal cortex (BA10) | L | −10 | 53 | 16 | 39 | 3.88 |
| Medial prefrontal cortex | R | 23 | 36 | 20 | 17 | 3.53 |
| Middle frontal gyrus | R | 43 | 30 | 20 | 32 | 3.73 |
| Precentral gyrus | R | 46 | −7 | 46 | 352 | 4.28 |
| Cuneus | L | −10 | −89 | 33 | 24 | 4.12 |