Table 2.

Estimates of the difference in neurocognitive Z-scores over time in children with cerebral malaria (CM), uncomplicated malaria (UM) and community children (CC) from the linear mixed effects model.

Variable	Difference in the Z-score	95% Confidence Interval	Unadjusted p-value
CM – CC at each time point
CM – CC: baseline	-1.14	(-1.51, -0.77)	< 0.0001
CM – CC: 3 months	-0.40	(-0.77, -0.02)	0.04
CM – CC: 6 months	-0.55	(-0.92, -0.17)	0.005
CM – CC: 2 years	-0.55	(-0.94, -0.17)	0.005
UM – CC at each time point
UM – CC: baseline	0.21	(-0.13, 0.56)	0.22
UM – CC: 3 months	0.26	(-0.09, 0.60)	0.15
UM – CC: 6 months	0.05	(-0.30, 0.40)	0.77
UM – CC: 2 years	0.02	(-0.33, 0.37)	0.91
CM trend over time
CM: 3 months – baseline	0.76	(0.54, 0.98)	< 0.0001
CM: 6 months – 3 months	-0.15	(-0.38, 0.07)	0.17
CM: 2 years – 6 months	-0.02	(-0.24, 0.21)	0.89