Figure 5. Moderate antagonism of AA-mediated hK_Ca3.1-inhibtion by 5,6-EET.

A) Time course of channel inhibition by 10 µM of AA in the presence of 1 µM 5,6-EET. B) Summary data of channel inhibition at 20 s after seal excision and with two concentrations (1 and 10 µM) of 5,6-EET and AA. Data are means ± SEM; numbers in the graphs indicate the number of inside-out experiments; *P<0.05 vs. AA alone, One-way ANOVA and Tukey post hoc test.