Table 2.
Distribution of mean biomarker levels overall and by gender in the SBES cohort. (n= 411)
| All participants (n = 411) | Males (n = 334) | Females (n = 77) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| N | Median | IQR | N | Median | IQR | N | Median | IQR | |
| CRPa (mg/L) | 398 | 1.90 | 0.95–3.60 | 329 | 1.80 | 0.90–3.35 | 69 | 2.95 | 1.7–4.35 |
| IL-6b (pg/ml) | 407 | 1.88 | 1.34–3.06 | 332 | 1.77 | 1.31–2.87 | 75 | 2.62 | 1.48–3.79 |
| sTNF- Receptor Ib (ng/ml) | 407 | 1.39 | 1.14–1.65 | 332 | 1.42 | 1.15–1.66 | 75 | 1.31 | 1.08–1.61 |
| sTNF- Receptor IIb (ng/ml) | 407 | 5.35 | 4.71–6.44 | 332 | 5.34 | 4.68–6.40 | 75 | 5.49 | 4.74–6.62 |
| Isoprostanesc(pg/ml) | 390 | 53 | 41–74 | 320 | 51 | 40–66 | 70 | 74 | 47–107 |
CRP was not measured in 4 people due to exhausted baseline plasma. CRP levels over 10 mg/L were excluded as per an apriori hypothesis. 4 people had plasma measured only at one time point and it was greater than 10 mg/L, 5 people had both CRP measurements greater than 10 mg/L.
IL-6 and TNF receptors were not measured in 4 people due to exhausted baseline plasma samples
Isoprostanes were not measured in 16 individuals due to exhausted baseline plasma samples, 5 samples were not successfully measured by the laboratory.
N = Number/frequency, IQR = Inter-quartile range, CRP = C-reactive protein, IL6 = Interleukin-6, sTNF-RI & II = soluble tumor necrotic factor receptor I & II