Table 4.

a. Adjusted Odds Ratio for mortality after controlling for reason for ventriculostomy, three percent saline, and TPN administration. Adjusted odds ratio for seizures by lowest sodium groups after controlling for reason for ventriculostomy and preexisting epilepsy.

	Mortality			Seizures
	OR	95% Confidence Interval	p-value	OR	95% Confidence Interval	p-value
Sodium > =135 meq/L	REF	REF	REF	REF	REF	REF
131-134 meq/L	0.55	0.16, 1.9	0.35	1.7	0.69, 4.3	0.25
<130 meq/L	0.52	0.08, 3.2	0.48	2.6	075, 9.4	0.13

b. Adjusted odds of mortality by for every increase in 3 of maximum daily change in sodium after controlling for three percent administration and total parental nutrition and ventriculostomy indication (TPN. meq/L: milliequivalents per liter) and change in sodium during EVD management after controlling for ventriculostomy indication, lowest sodium group, three percent and total parental nutrition (TPN).
	In-hospital mortality
	OR	95% Confidence Interval	p-value
Maximum daily Change in Sodium (by 3 meq/L)	1.38	1.06, 1.8	0.016
Change in Sodium (by 3 meq/L)	1.59	1.2, 2.11	0.001