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. 2014 Nov 5;9(11):e112378. doi: 10.1371/journal.pone.0112378

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© 2014 Sang et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Type I IFN functional gene (pseudogene) numbers in different animal species imply gene expansion of porcine type I IFN genes. (B) Distribution of porcine type I IFN genes in the current porcine genome assembly. There are 18 duplicates (labeled in red), each identical to one of the previously identified IFN genes; therefore, there are 39 parsimoniously non-redundant porcine type I IFN genes plus 18 duplicates resulting either from very recent gene duplication events or artifactual assembly. Gene symbol legend: black, functional genes; grey, pseudogenes; red, duplications to the indicated ones (for examples, IFNA1L has 99–100% sequence identity to IFNA1; dashed line, unassembled piece. KLHL9, kelch-like protein 9-like gene in the middle of type I IFN gene locus.