Figure 2. LKB1 loss in endometrial cancers confer increased cell proliferation and decreased apoptosis.
A) ECC-1 and KLE cells were transfected with LKB1 siRNA and vector expressing full-length LKB1 (LKB1-pCMV) respectively. After 72 h, B) MTT assay and C) cytoplasmic DNA fragmentation ELISA were used to measure the proliferation rate and apoptosis induction respectively.