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. Author manuscript; available in PMC: 2015 Nov 1.
Published in final edited form as: Mol Cancer Ther. 2014 Sep 19;13(11):2653–2661. doi: 10.1158/1535-7163.MCT-14-0132

Table 1.

Sensitivity of TNBC cell lines to mesothelin-targeted RITs

RIT HCC70 SUM149
IC50 (ng/mL) IC50 (pM) N IC50 (ng/mL) IC50 (pM) N
SS1P 4.6 ± 3.2 74.1 ± 52.0 9 15.7 ± 9.8 252 ± 158 3
SS1-LR 0.94 ± 0.56 19.6 ± 11.7 5 1.5 ± 1.4 30.2 ± 29.1 2
RG7787 3.4 ± 2.8 45.2 ± 37.9 10 4.8 ± 1.3 64.8 ± 17.9 3

Sensitivity of HCC70 and SUM149 TNBC cell lines is reported in IC50 values ± standard deviation for SS1P, SS1-LR and RG7787 RITs. N = number of times each experiment was repeated with six replicates in each experiment.