Fig. 4.
sVEGFR-3 treatment prolongs corneal allograft survival. BALB/c recipient mice received C57BL/6 corneal grafts and were treated intra-peritoneally with sVEGFR-3 or PBS starting the day of transplantation up to 8 weeks once every other day. Graft survival was followed biomicroscopically and a Kaplan–Meier curve was plotted to compare the survival in the two study groups. The log-rank test was used for statistical analysis. sVEGFR-3-treated mice showed a survival rate of 87.5 % (n=16) compared to a 50 % survival rate in PBS-treated mice (n= 10)