Predicted miR-340 targets are oval and outlined in a solid line and targets found to be predicted and regulated by miR-340 are oval and outlined in a dashed line. MAPK components not predicted to be targeted by miR-340 are depicted as a solid outlined hexagon. miR-340 target predictions are based on prediction overlap between at least 4 of 6 miRNA target prediction databases including DIANAmT, miRanda, miRDB, miRWalk, RNA22, and TargetScan.