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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Arch Biochem Biophys. 2014 Aug 7;563:136–144. doi: 10.1016/j.abb.2014.07.026

Figure 7. Schematic Models For Primary Structures of Typical KRAB–Domains.

Figure 7

KRAB domains can be divided into three groups depending on their interactions with MAGE and KAP1: Group 1 (KRAB A+B) is repressed by KRAB domains and de-repressed by MAGE; Group 2 (KRAB A, KRAB A+b) is repressed by KRAB domains but not rescued by MAGE; Group 3 (SCAN, SCAN+KRAB A+B, KRAB A+SCAN+KRAB A) is not repressed by KRAB domains and is not affected by MAGE.