Table 1.
Number of genes associated with changes in histone modifications*
| Histone modification | Post-mating changes in young flies | Post-mating changes in aged flies | Changes associated with aging in virgin flies | Changes associated with aging in mated flies | ||||
|---|---|---|---|---|---|---|---|---|
| Histone peaks | Genes | Histone peaks | Genes | Histone peaks | Genes | Histone peaks | Genes | |
| H3K4me1 | ||||||||
| Up-regulated | 178 | 536 | 259 | 847 | 253 | 750 | 284 | 911 |
| Down-regulated | 205 | 677 | 249 | 772 | 291 | 971 | 299 | 1002 |
| H3K4me3 | ||||||||
| Up-regulated | 281 | 959 | 530 | 1899 | 611 | 2000 | 703 | 2482 |
| Down-regulated | 383 | 1293 | 482 | 1708 | 693 | 2382 | 710 | 2534 |
| H3K9ac | ||||||||
| Up-regulated | 512 | 1618 | 427 | 1427 | 816 | 2376 | 806 | 2598 |
| Down-regulated | 536 | 1680 | 458 | 1428 | 823 | 2553 | 834 | 2755 |
*Differences between conditions were estimated by subtracting histone peak amplitudes in virgin flies from those in mated flies and in young flies from those in aged flies. Only histone modification peaks that are significantly variable across the four conditions (FDR <0.05) with differences that are larger than one pooled standard deviation are counted.