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. 2014 Oct 20;7:737. doi: 10.1186/1756-0500-7-737

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© Showa et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Plots of viral levels against time under different immune response models. Neutralizing antibodies are not very efficient in controlling viral levels. The antibody response model yielded levels that settled to levels comparable to those of the basic model (model without immune system intervention). Lowest viral levels are obtained when all the specific immune system components work simultaneously as is shown by the graph of the combined model. Killing of infected cells also play a very crucial role in reducing the viral levels as can be seen from the graph of the lytic model. The parameter values used are given in Table 1 and the initial conditions were .

Inline graphic — Plots of viral levels against time under different immune response models. Neutralizing antibodies are not very efficient in controlling viral levels. The antibody response model yielded levels that settled to levels comparable to those of the basic model (model without immune system intervention). Lowest viral levels are obtained when all the specific immune system components work simultaneously as is shown by the graph of the combined model. Killing of infected cells also play a very crucial role in reducing the viral levels as can be seen from the graph of the lytic model. The parameter values used are given in Table 1 and the initial conditions were .