Table 2.
Brain magnetic resonance imaging (MRI) volumes in patients with type 2 diabetes mellitus (T2DM) and healthy participants
| MRI variable | T2DM | Healthy | Association of T2DM with MRI variable | P for regression |
|---|---|---|---|---|
| Mean ± SD (n = 37) | Mean ± SD (n = 37) | β coefficient (95% CI) | ||
| Gray matter volume (ml) | 567.36 ± 77.81 | 607.81 ± 63.01 | 0.014 (−17.23, 21.21) | 0.84 |
| White matter volume (ml) | 583.92 ± 76.03 | 604.84 ± 80.53 | −0.005 (−15.98, 14.48) | 0.92 |
| Left hippocampal volume (ml) | 2.43 ± 0.37 | 2.55 ± 0.38 | −0.019 (−0.17, 0.14) | 0.86 |
| Right hippocampal volume (ml) | 2.51 ± 0.36 | 2.56 ± 0.39 | 0.046 (−0.14, 0.21) | 0.70 |
| White matter lesion volume (ml) | 3.34 ± 2.38 | 3.44 ± 2.39 | −0.148 (−1.93, 0.54) | 0.26 |
Unadjusted MRI volumes are presented in the first two columns; β refers to standardized beta coefficient for the association between T2DM and MRI variables determined by ANCOVA and adjusted for age, sex and total intracranial volume. P value is for relation of diabetes status with MRI variables.