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. 2014 Oct 24;14:781. doi: 10.1186/1471-2407-14-781

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© Zou et al.; licensee BioMed Central Ltd. 2014

This article is published under license to BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Increased CXCL1 RNA expression in breast cancer stroma is associated with poor prognosis. CXCL1 RNA expression values were obtained from the Finak microarray database, and analyzed for the following. A. The percentage of patients negative or positive for CXCL1 expression exhibiting tumor recurrence over time. The fractions below the graph depict recurrence-free patients over the total number of CXL1 negative or CXCL1 positive patients. B. Associations with overall tumor recurrence after 5 years. C. Associations with decreased survival after 5 years. Statistical analysis was performed using the Log-rank Test (A) or Wilcoxon Two-Sample Test (B and C). Mean ± SD. Statistical significance was determined by p <0.05. *p ≤0.001, ***p≥0.05.