Table 2.
Relationship between known prognostic factors and CXCL1 protein expression in breast cancer stroma
| Factor | r | 95% CI | p-value | n |
|---|---|---|---|---|
| Age | 0.12 | -0.03 to 0.40 | 0.08 | 79 |
| tumor size | 0.18 | -0.11 to 0.44 | 0.19 | 51 |
| BCL2 | -0.06 | -0.40 to 0.29 | 0.72 | 34 |
| P53 | 0.08 | -0.23 to 0.38 | 0.60 | 43 |
| Ki67 | 0.25 | -0.07 to 0.51 | 0.12 | 41 |
| ER | -0.07 | -0.37 to 0.24 | 0.70 | 42 |
| PR | 0.10 | -0.22 to 0.40 | 0.51 | 42 |
| HER2 | 0.14 | -0.19 to 0.44 | 0.40 | 40 |
| EGFR | 0.07 | -0.26 to 0.39 | 0.63 | 38 |
| No. of lymph node metastases | 0.17 | -0.14 to 0.45 | 0.28 | 23 |
Association between CXCL1 protein expression and commonly used prognostic markers was determined in DCIS and IDC stromal tissues using Spearman Correlation analysis. Significance was determined by p<0.05. r= correlation coefficient.