Table 4.
Signaling component | r | 95% CI | p-value | n |
---|---|---|---|---|
TGF-β | -0.33 | -0.52 to -0.09 | 0.01 | 69 |
p-Smad2 | -0.25 | -0.44 to -0.027 | 0.02 | 80 |
p-Smad3 | -0.32 | -0.50 to -0.10 | <0.01 | 81 |
Spearman Correlation used to determine the association between expression of CXCL1 and expression of TGF-β signaling components in normal and breast cancer stroma. Normal stroma refers to samples from both reduction mammoplasty and adjacent breast tissue.
Significance was determined by p<0.05. r= correlation coefficient.