Table 3.

Summary of univariate and multivariate Poisson regression analysis of relationship between PF13 and MSP1 antibody response with incidence rate of malaria attacks in Ndiop

	Univariate individual antigen analysis			PF13 and MSP1p19 adjusted model			PF13 and MSP1p19 model adjusted for age
	OR	95% CI	P	OR	95% CI	P	OR	95% CI	P
ELISA OD
PF13	0.70	[0.6-0.9]	<0.01	0.89	[0.74-1.1]	0.25	0.88	[0.7-1.1]	0.19
MSP1	0.46	[0.37-0.59]	<0.01	0.49	[0.38-0.62]	<0.001	0.81	[0.62-1.1]	0.12
MFI
PF13	0.99	[0.99-0.99]	0.02	0.99	[0.99-1.0]	0.12	0.99	[0.99-1.0]	0.06
MSP1	0.99	[0.99-0.99]	<0.01	0.99	[0.99-0.99]	<0.01	0.99	[0.99-1.0]	0.58
OD ratio
PF13	0.96	[0.94-0.98]	<0.01	0.98	[0.96-1.0]	0.06	0.98	[0.96-1.0]	0.08
MSP1	0.88	[0.85-0.92]	<0.01	0.89	[0.86-0.93]	<0.001	0.97	[0.93-1.0]	0.13
MFI ratio
PF13	0.98	[0.97-0.99]	0.02	0.99	[0.9-1.0]	0.11	0.98	[0.97-1.0]	0.06
MSP1	0.95	[0.93-0.97]	<0.01	0.95	[0.93-0.98]	<0.01	0.99	[0.96-1.0]	0.52
Dichotomized antibody response according to OD ratio threshold
PF13 positivity	0.79	[0.60-1.04]	0.10	0.98	[0.74-1.30]	0.90	1.2	[0.86-1.6]	0.30
MSP1 positivity	0.44	[0.34-0.57]	<0.01	0.44	[0.33-0.57]	<0.001	0.71	[0.53-0.93]	0.01
Dichotomized antibody response according to MFI Ratio threshold
PFf13 positivity	0.83	[0.63-1.1]	0.17	1.01	[0.7-1.4]	0.91	1.08	[081–1.45]	0.57
MSP1 positivity	0.61	[0.47-0.79]	<0.01	0.61	[0.4-0.8]	<0.001	0.89	[0.67-1.18]	0.43
Dichotomized antibody response according with ROC threshold
PF13 positivity	0.70	[0.5-0.9]	0.03	0.89	[0.7-1.2]	0.48	1.1	[0.8-1.5]	0.48
MSP1 positivity	0.78	[0.60-1.02]	0.07	0.82	[0.6-1.1]	0.21	1.05	[0.78-1.4]	0.75