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. 2014 Oct 29;11:186. doi: 10.1186/s12974-014-0186-3

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© Noailles et al.; licensee BioMed Central Ltd. 2014

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Number and distribution of macrophages in the ganglion cell layer (GCL). (A- C) Representative images of whole-mount rat retinas from a SD (A), untreated P23H (B ) and tauroursodeoxycholic acid (TUDCA)-treated P23H rat (C) labeled with immunoperoxidase. (D, E) Density of macrophages, expressed as number of cells per mm², in each of 12 representative regions in each retina: 6 equidistantly arranged on the superior-inferior axis of the retina (D) and 6 disposed on the temporal-nasal axis (E). The scheme in the margin of each panel represents the position in the retina of each representative region analyzed. Scale bar: 40 μm.