Table 6.
Type of Financial Tie and Voting in Favor of Sponsor, Non-unanimous Votes
| Financial Relationship | Favor Sponsor Versus Not Favor Sponsor Odds (95% CI) p-value | Difference Between Financial Tie and No Financial Tie Odds Ratio (95% CI) p-value |
|---|---|---|
| Research (Investigator or Grant/Contract Recipient) | ||
| Sponsor only | 2.34 | 2.14 |
| (0.53,10.30) | (0.48,9.54) | |
| p = 0.261 | p = 0.317 | |
| Competitor only | 0.58 | 0.53 |
| (0.19,1.78) | (0.17,1.63) | |
| p = 0.339 | p = 0.269 | |
| Both sponsor and competitor | .. | .. |
| Employer Grant or Contract | ||
| Sponsor only | 0.97 | 0.89 |
| (0.40,2.37) | (0.37,2.18) | |
| p = 0.955 | p = 0.803 | |
| Competitor only | 1.30 | 1.19 |
| (0.69,2.45) | (0.62,2.29) | |
| p = 0.425 | p = 0.608 | |
| Both sponsor and | 0.35 | 0.32 |
| competitor | (0.02,5.03) | (0.02,4.60) |
| p = 0.441 | p = 0.404 | |
| Ownership Interest (eg, Stock), Income from Royalties or Licenses | ||
| Sponsor only | 2.07* | 1.89* |
| (1.10,3.90) | (0.99,3.64) | |
| p = 0.025 | p = 0.055 | |
| Competitor only | 1.34* | 1.23 |
| (0.95,1.88) | (0.85,1.77) | |
| p = 0.092 | p = 0.276 | |
| Both sponsor and | 1.11 | 1.02 |
| competitor | (0.34,3.63) | (0.31,3.35) |
| p = 0.862 | p = 0.977 | |
| Consulting | ||
| Sponsor only | .. | .. |
| Competitor only | .. | .. |
| Both sponsor and | 0.98 | 0.89 |
| competitor | (0.69,1.38) | (0.62,1.29) |
| p = 0.894 | p = 0.552 | |
| Member of Advisory Board or Steering Committee | ||
| Sponsor only | 5.43*** | 4.97*** |
| (1.78,16.55) | (1.62,15.29) | |
| p = 0.003 | p = 0.005 | |
| Competitor only | 1.55 | 1.42 |
| (0.98,2.47) | (0.88,2.31) | |
| p = 0.062 | p = 0.153 | |
| Both sponsor and competitor | .. | .. |
| Blinded Endpoint Reviewer or Member of Data Safety Monitoring Board | ||
| Sponsor only | 0.31 | 0.28 |
| (0.03,2.95) | (0.03,2.72) | |
| p = 0.305 | p = 0.272 | |
| Competitor only | 0.25** | 0.23** |
| (0.08,0.79) | (0.07,0.73) | |
| p = 0.018 | p = 0.012 | |
| Both sponsor and | 1.83 | 1.68 |
| competitor | (0.17,20.21) | (0.15,18.55) |
| p = 0.621 | p = 0.673 | |
| Paid speaker | ||
| Sponsor only | 1.99* | 1.82* |
| (0.99,4.00) | (0.90,3.70) | |
| p = 0.053 | p = 0.096 | |
| Competitor only | 1.78* | 1.63 |
| (0.94,3.38) | (0.85,3.13) | |
| p = 0.078 | p = 0.143 | |
| Both sponsor and | 0.46 | 0.42* |
| competitor | (0.18,1.18) | (0.17,1.08) |
| p = 0.106 | p = 0.073 | |
| No financial ties to either | 1.09* | ref |
| sponsor or competitor | (0.99,1.21) | |
| p = 0.083 | ||
| Number of Question-Votes | 9,717 | |
| Number of voting participants | 1,236 | |
| Number of questions | 699 | |
Indicates insufficient variability to identify coefficient.
***p < 0.01, **p < 0.05, *p < 0.10. Standard errors clustered on question.