Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
The estrogen metabolite 2-hydroxyestrogen (2-OHE2) reduces estrogen-mediated transactivation in human myometrial cells. Bars represent average luciferase activities (with the standard error of the mean) from two independent assays in which samples were tested in triplicate. The inhibitory effect of 2-OHE2 was statistically significant (P=.002) at doses of 5 μmol/L and higher as indicated by an asterisks.
Wentz. Catechol-O-Methyl Transferase Regulation. Obstet Gynecol 2006.
