Table 1.
Dysfunction pathways between human T2D islet cells and normal islet cells.
| Pathway | Count | P value |
|---|---|---|
| Eicosanoid synthesis | 3 | 0.0016 |
| MAPK signaling pathway | 7 | 0.0029 |
| IL-6 signaling pathway | 4 | 0.005 |
| Integrated Pancreatic Cancer Pathway | 7 | 0.0055 |
| Mitochondrial LC-Fatty Acid Beta-Oxidation | 2 | 0.0152 |
| Complement and Coagulation Cascades | 3 | 0.0205 |
| Focal adhesion | 6 | 0.021 |
| Selenium Pathway | 4 | 0.0316 |
| IL-7 signaling pathway | 2 | 0.0354 |
| TGF-beta signaling pathway | 3 | 0.0362 |
| IL-1 signaling pathway | 3 | 0.0377 |
| Fatty Acid Biosynthesis | 2 | 0.0436 |
| Tryptophan metabolism | 3 | 0.0441 |
| Inflammatory Response Pathway | 2 | 0.0464 |
| Prostaglandin Synthesis and Regulation | 2 | 0.0494 |