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Scanning electron micrographs of the substrates at day 28. (a–d) Osteoclast-like cells visible across the planar surfaces showing interactions with ceramic grains. (d) Podosomes were visible (arrow) on some of the osteoclasts. (e) Few osteoclast-like cells with pit bridging by macrophage-like cells (f, g) The bridging cells retracting over the pits, leaving retraction fibres (outset in (f)). Macrophage filopodia were also seen to interact with the grain but not the pits (h).
