Table 1 . General Clinical Information and Biochemical indicators of Patients and Control Groups a,b.
Parameters | Control | MS | CAD | CAD + MS | P Value |
---|---|---|---|---|---|
Case, No. | 30 | 30 | 30 | 30 | |
Age, y | 51 ± 11 | 53 ± 11 | 66 ± 9 | 61 ± 11 | < 0.001 |
Gender, % | |||||
Male | 73 | 77 | 77 | 43 | 0.026 |
BMI, kg/m 2 | 21.1 ± 1.5 | 25.6 ± 1 | 23.7 ± 1.3 | 27.2 ± 1.3 | < 0.001 |
SBP, mmHg | 124 ± 8 | 136 ± 6 | 129 ± 10 | 142 ± 9 | < 0.001 |
DBP, mmHg | 72 ± 5 | 74 ± 7 | 77 ± 7 | 82 ± 7 | < 0.001 |
TG, mmol/L | 0.84 ± 0.3 | 2.3 ± 1.2 | 1.7 ± 1.6 | 2.1 ± 1.4 | < 0.001 |
TC, mmol/L | 4.2 ± 0.7 | 4.9 ± 1.1 | 4.1 ± 1.3 | 4.5 ± 1.1 | 0.015 |
HDL-C, mmol/L | 1.7 ± 0.3 | 1.4 ± 0.3 | 1.4 ± 0.8 | 1.3 ± 0.4 | 0.001 |
LDL-C, mmol/L | 1.9 ± 0.6 | 2.4 ± 0.9 | 2.3 ± 1.0 | 2.3 ± 1.0 | 0.156 |
FBS, mmol/L | 4.5 ± 0.3 | 5.9 ± 0.6 | 5.0 ± 0.7 | 6.2 ± 0.7 | < 0.001 |
AST, U/L | 11.2 ± 3.6 | 18.3 ± 4.3 | 21.2 ± 5.4 | 23.5 ± 4.8 | < 0.001 |
ALT, U/L | 14.5 ± 4.5 | 19.0 ± 4.0 | 20.9 ± 5.6 | 21.2 ± 4 | < 0.001 |
BUN, mmol/L | 3.9 ± 0.6 | 4.8 ± 1.4 | 5.5 ± 0.9 | 5.3 ± 1 | < 0.001 |
Cr, mg/L | 71.0 ± 9.8 | 83.5 ± 10.6 | 85.8 ± 14.1 | 89.3 ± 16 | < 0.001 |
UA, mmol/L | 251.9 ± 42 | 307.0 ± 60.0 | 285.7 ± 53.5 | 314.7 ± 55.1 | < 0.001 |
hs-CRP, mg/L | 0.7 ± 0.8 | 1.7 ± 2.9 | 7.2 ± 9.8 | 12.0 ± 8.5 | < 0.001 |
a Results were mean ± SD. Values in a same row with different superscripts were significantly different (P < 0.05).
b Abbreviations: ALT; alanine transaminase, AST; aspartate aminotransferase, BMI; body mass index, BUN; blood urine nitrogen, CAD; coronary artery disease, Cr; creatinine, DBP; Diastolic blood pressure, FBS; fasting blood sugar, LDL; low density lipoprotein, HDL; high density lipoprotein, MS; metabolic syndrome, SBP; systolic blood pressure, TG; triglyceride, TC; total cholesterol, UA; uric acid.